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Ang4 Antibody

  • 货号：
    CSB-PA661010ZA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: Ang4 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31.4 kDa
      Observed band size: 33 kDa
  • 其他：

产品详情

  • Uniprot No.：
    Q3TMQ6
  • 基因名：
    Ang4
  • 别名：
    Angiogenin-4 (EC 3.1.27.-), Ang4
  • 反应种属：
    Mus musculus (Mouse)
  • 免疫原：
    Recombinant Mus musculus (Mouse) Angiogenin-4 (25-144aa)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Ang4 Antibody (CSB-PA661010ZA01MO)，的标记方式是Non-conjugated。对于Ang4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA661010ZB01MO Ang4 Antibody, HRP conjugated ELISA
    FITC CSB-PA661010ZC01MO Ang4 Antibody, FITC conjugated
    Biotin CSB-PA661010ZD01MO Ang4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro).
  • 基因功能参考文献：
    1. Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge. PMID: 24358364
    2. The cellular source of mouse Ang4 in the colon following T. muris infection is the goblet cell and expression is under the control of IL-13. PMID: 22970115
    3. Expression of Reg3 proteins and Ang4 by goblet cells point to an important role for goblet cells in innate defense. PMID: 22723890
    4. differences in gene expression profiles associated with immune and defence responses, including angiogenin 4 PMID: 19852835
    5. protein structure of angiogenin 4 PMID: 15772759

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  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus.
  • 蛋白家族：
    Pancreatic ribonuclease family
  • 组织特异性：
    Detected in small intestine, caecum and colon, with the highest expression in Paneth cells in the intestinal epithelium.
  • 数据库链接：

    KEGG: mmu:219033

    STRING: 10090.ENSMUSP00000073525

    UniGene: Mm.343899