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Adh7 Antibody

  • 货号：
    CSB-PA717544LA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue
      All lanes: Adh7 antibody at 3.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 40 kDa
      Observed band size: 40 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Adh7 Polyclonal antibody
  • Uniprot No.：
    Q64437
  • 基因名：
    Adh7
  • 别名：
    Adh7 antibody; Adh-3 antibody; Adh3All-trans-retinol dehydrogenase [NAD(+)] ADH7 antibody; EC 1.1.1.105 antibody; ADH-C2 antibody; Alcohol dehydrogenase 7 antibody; Alcohol dehydrogenase class 4 mu/sigma chain antibody; EC 1.1.1.1 antibody; Alcohol dehydrogenase class IV mu/sigma chain antibody; Gastric alcohol dehydrogenase antibody; Omega-hydroxydecanoate dehydrogenase ADH7 antibody; EC 1.1.1.66 antibody; Retinol dehydrogenase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse
  • 免疫原：
    Recombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Adh7 Antibody (CSB-PA717544LA01MO)，的标记方式是Non-conjugated。对于Adh7 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA717544LB01MO Adh7 Antibody, HRP conjugated ELISA
    FITC CSB-PA717544LC01MO Adh7 Antibody, FITC conjugated
    Biotin CSB-PA717544LD01MO Adh7 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.
  • 基因功能参考文献：
    1. ADH3 promotes liver fibrosis by enhancing hepatic stellate cell activation and inhibiting natural killer cell activity PMID: 24668648
    2. Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3 PMID: 11959987
    3. ADH1 functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity, ADH3 plays a secondary role PMID: 12027900
    4. Cellular expression of Adh3 in the GUI tract was studied. PMID: 17257171
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Zinc-containing alcohol dehydrogenase family, Class-IV subfamily
  • 组织特异性：
    High expression in the stomach mucosa. Lower expression in eye, thymus, skin and ovary. Very low expression in small intestine, liver and uterus.
  • 数据库链接：

    KEGG: mmu:11529

    STRING: 10090.ENSMUSP00000087633

    UniGene: Mm.8473