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ATP5L Antibody

  • 货号:
    CSB-PA002374GA01HU
  • 规格:
    ¥3,900
  • 其他:

产品详情

  • Uniprot No.:
    O75964
  • 基因名:
  • 别名:
    ATP synthase subunit g antibody; ATP synthase; H+ transporting; mitochondrial F1F0; subunit g antibody; ATP synthase; H+ transporting; mitochondrial Fo complex; subunit G antibody; ATP5L antibody; ATP5L_HUMAN antibody; ATPase subunit g antibody; F1Fo ATP synthase complex Fo membrane domain g subunit antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse,Rat
  • 免疫原:
    Human ATP5L
  • 免疫原种属:
    Homo sapiens (Human)
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB,IHC
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
  • 基因功能参考文献:
    1. this study demonstrates that F1Fo ATP synthase can support general mitochondrial and cellular functions, working in extremely efficient 'energy saving' reverse mode and flexibly recruiting free radical detoxication and ATP producing / transporting pathways. PMID: 28189850
    2. Overexpression of miR-570-3p in platelets resulted in reduced levels of ATP5L mRNA and concomitant ATP loss. PMID: 27561077
  • 亚细胞定位:
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族:
    ATPase g subunit family
  • 数据库链接:

    HGNC: 14247

    OMIM: 617473

    KEGG: hsa:10632

    STRING: 9606.ENSP00000300688

    UniGene: Hs.486360