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ATP5I Antibody

  • 货号：
    CSB-PA000954
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using ATP5I Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P56385
  • 基因名：
  • 别名：
    ATP 5I antibody; ATP 5K antibody; ATP synthase e chain mitochondrial antibody; ATP synthase H+ transporting mitochondrial F0 complex subunit E antibody; ATP synthase subunit e antibody; ATP synthase subunit e mitochondrial antibody; ATP5I antibody; ATP5I_HUMAN antibody; ATP5K antibody; ATPase subunit e antibody; F1F0 ATP synthase murine e subunit antibody; MGC12532 antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ATP5I.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
  • 基因功能参考文献：
    1. results suggest that antisense of hAS-e can inhibit cell proliferation through the MAP kinase pathway PMID: 11939412
    2. This is the first report identifying caspase-3 as a substrate protein of Hsp90. PMID: 16682002
    3. The inhibitory activity against mitochondria and F(1)F(0)-ATP synthase is not limited to atrazine but is likely to be applicable to other triazine-based compounds. PMID: 18060860
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    ATPase e subunit family
  • 数据库链接：

    HGNC: 846

    OMIM: 601519

    KEGG: hsa:521

    STRING: 9606.ENSP00000306003

    UniGene: Hs.85539