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ATP5F1D Antibody

  • 货号：
    CSB-PA00635A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ATP5F1D antibody at 2µg/ml
      Lane 1: EC109 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 18 kDa
      Observed band size: 18 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA00635A0Rb at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA00635A0Rb at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ATP5D Polyclonal antibody
  • Uniprot No.：
    P30049
  • 基因名：
  • 别名：
    ATP synthase subunit delta; mitochondrial antibody; ATP synthase subunit delta; mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F1 complex; delta subunit antibody; ATP5D antibody; ATPD_HUMAN antibody; F ATPase delta subunit antibody; F-ATPase delta subunit antibody; Mitochondrial ATP synthase complex delta subunit precusor antibody; Mitochondrial ATP synthase delta subunit antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ATP synthase subunit delta, mitochondrial protein (32-158AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ATP5F1D Antibody (CSB-PA00635A0Rb)，的标记方式是Non-conjugated。对于ATP5F1D Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA00635B0Rb ATP5F1D Antibody, HRP conjugated ELISA
    FITC CSB-PA00635C0Rb ATP5F1D Antibody, FITC conjugated
    Biotin CSB-PA00635D0Rb ATP5F1D Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
  • 基因功能参考文献：
    1. These data establish c.245C>T (p.Pro82Leu) and c.317T>G (p.Val106Gly) in ATP5F1D as pathogenic variants leading to a Mendelian mitochondrial disease featuring episodic metabolic decompensation. PMID: 29478781
    2. Immunohistochemical and immunofluorescent double staining of ATP5D and synaptophysin showed that the reduction of ATP5D was most pronounced at synapses in amyotrophic lateral sclerosis PMID: 27899032
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    ATPase epsilon chain family
  • 数据库链接：

    HGNC: 837

    OMIM: 603150

    KEGG: hsa:513

    STRING: 9606.ENSP00000215375

    UniGene: Hs.418668