ATP4B Antibody
产品详情
-
产品名称:Rabbit anti-Homo sapiens (Human) ATP4B Polyclonal antibody
-
Uniprot No.:P51164
-
基因名:
-
别名:Gastric H(+)/K(+) ATPase subunit beta antibody; ATP4B antibody; ATP4B_HUMAN antibody; ATP6B antibody; ATPase H+/K+ exchanging beta polypeptide antibody; ATPase H+/K+ transporting beta polypeptide antibody; Gastric H K ATPase catalytic subunit antibody; Gastric H(+)/K(+) ATPase subunit beta antibody; Gastric H+/K+ ATPase beta subunit antibody; Gastric hydrogen potassium ATPase antibody; Gastric hydrogen potassium ATPase beta antibody; Hydrogen/potassium exchanging ATPase 4B antibody; OTTHUMP00000178856 antibody; Parietal cell antigen antibody; Potassium transporting ATPase beta chain antibody; Potassium transporting ATPase subunit beta antibody; Potassium-transporting ATPase subunit beta antibody; Proton pump antibody; Proton pump beta chain antibody
-
宿主:Rabbit
-
反应种属:Human
-
免疫原:Recombinant Human Potassium-transporting ATPase subunit beta protein (58-291AA)
-
免疫原种属:Homo sapiens (Human)
-
标记方式:Non-conjugated
本页面中的产品,ATP4B Antibody (CSB-PA002343EA01HU),的标记方式是Non-conjugated。对于ATP4B Antibody,我们还提供其他标记。见下表:
-
克隆类型:Polyclonal
-
抗体亚型:IgG
-
纯化方式:>95%, Protein G purified
-
浓度:It differs from different batches. Please contact us to confirm it.
-
保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
-
应用范围:ELISA
-
Protocols:
-
储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
-
功能:The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump. Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle.
-
基因功能参考文献:
- these findings demonstrated that a decrease in pHi, caused by H+/K+-ATPase inhibition induced by BMT-1, triggered the dysfunction of the mitochondria resulting in the apoptosis of MM cells PMID: 24700195
- Downregulation of ATP4B gene is associated with gastric cancer. PMID: 23317218
- BCL-2 inhibits formation of reactive oxygen species. PMID: 11865975
- Content of the beta1 subunit of sodium potassium pump in resistance trained control subjects was 33% higher in trained compared to untrained leg, and 47% higher in trained compared to untrained leg in diabetics. PMID: 14685860
- Thus prolonged exhaustive exercise impaired each of the maximal in vitro Na+-K+-ATPase activity, Ca2+ release, and Ca2+ uptake rates. PMID: 15155714
- Use of fold recognition methods enables the prediction that a C-terminal domain of the beta subunits of Na,K-ATPase and H,K-ATPase has an immunoglobulin-like fold, which resembles cell adhesion molecules. PMID: 19694409
显示更多
收起更多
-
亚细胞定位:Apical cell membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
-
蛋白家族:X(+)/potassium ATPases subunit beta family
-
数据库链接:
HGNC: 820
OMIM: 137217
KEGG: hsa:496
STRING: 9606.ENSP00000334216
UniGene: Hs.434202
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-