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ASGR2 Antibody

  • 货号：
    CSB-PA002208ZA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: ASGR2 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 45.9 kDa
      Observed band size: 52 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P24721
  • 基因名：
  • 别名：
    Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (HL-2) (mHL-2), Asgr2, Asgr-2
  • 反应种属：
    Ugandan cassava brown streak virus
  • 免疫原：
    Recombinant Mouse Asialoglycoprotein receptor 2 (Asgr2), Partial (80-301AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
  • 基因功能参考文献：
    1. ASGP-R2 mediates the clearance of glycoproteins that bear oligosaccharides terminating with Siaalpha2,6Gal and thereby helps maintain the relative concentrations of these glycoproteins in the blood. PMID: 19075021
  • 亚细胞定位：
    Membrane; Single-pass type II membrane protein.
  • 组织特异性：
    Expressed exclusively in hepatic parenchymal cells.
  • 数据库链接：

    KEGG: mmu:11890

    STRING: 10090.ENSMUSP00000099632

    UniGene: Mm.1357