Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. ASCC2 Antibody

ASCC2 Antibody

  • 货号：
    CSB-PA002197GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9H1I8
  • 基因名：
    ASCC2
  • 别名：
    1700011I11Rik antibody; 2610034L15Rik antibody; Activating signal cointegrator 1 complex subunit 2 antibody; AI482016 antibody; ASC 1 complex subunit p100 antibody; ASC-1 complex subunit p100 antibody; ASC1P100 antibody; ASCC 2 antibody; Ascc2 antibody; ASCC2_HUMAN antibody; AW046480 antibody; FLJ21588 antibody; OTTMUSP00000005258 antibody; p100 antibody; RGD1561422 antibody; RP23-280J3.3 antibody; Trip4 complex subunit p100 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ASCC2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT) complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes.
  • 亚细胞定位：
    Nucleus. Nucleus speckle.
  • 蛋白家族：
    ASCC2 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 24103

    OMIM: 614216

    KEGG: hsa:84164

    STRING: 9606.ENSP00000305502

    UniGene: Hs.731754