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ARMT1 Antibody

  • 货号：
    CSB-PA867178LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ARMT1 antibody at 0.6µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: A431 whole cell lysate
      Lane 3: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 52 kDa
      Observed band size: 52 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA867178LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA867178LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA867178LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA867178LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ARMT1 Polyclonal antibody
  • Uniprot No.：
    Q9H993
  • 基因名：
    ARMT1
  • 别名：
    ARMT1 antibody; C6orf211Damage-control phosphatase ARMT1 antibody; EC 3.1.3.- antibody; Acidic residue methyltransferase 1 antibody; Protein-glutamate O-methyltransferase antibody; EC 2.1.1.- antibody; Sugar phosphate phosphatase ARMT1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein-glutamate O-methyltransferase protein (2-250AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ARMT1 Antibody (CSB-PA867178LA01HU)，的标记方式是Non-conjugated。对于ARMT1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA867178LB01HU ARMT1 Antibody, HRP conjugated ELISA
    FITC CSB-PA867178LC01HU ARMT1 Antibody, FITC conjugated
    Biotin CSB-PA867178LD01HU ARMT1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
  • 基因功能参考文献：
    1. Studies show that acidic residue methyltransferase 1 (Armt1) has a vital role in regulation of the DNA damage response likely through its ability to O-methylate glutamyl residues of the DNA repair factor proliferating cell nuclear antigen (PCNA). PMID: 26450907
    2. Armt1 protein specifically targets proliferating cell nuclear antigen (PCNA) in breast cancer cells, predominately methylating glutamate side chains. PMID: 25732820
    3. C6ORF211 correlates with proliferation and clinical outcome in tumors. PMID: 21552322
  • 蛋白家族：
    ARMT1 family
  • 数据库链接：

    HGNC: 17872

    OMIM: 616332

    KEGG: hsa:79624

    STRING: 9606.ENSP00000356263

    UniGene: Hs.15929