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APOOL Antibody

  • 货号：
    CSB-PA001949LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001949LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA001949LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA001949LA01HU at dilution of 1:100
    • Immunofluorescence staining of U251 cells with CSB-PA001949LA01HU at 1:155,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) APOOL Polyclonal antibody
  • Uniprot No.：
    Q6UXV4
  • 基因名：
    APOOL
  • 别名：
    AAIR8193 antibody; Apolipoprotein O-like antibody; APOOL antibody; APOOL_HUMAN antibody; CXorf33 antibody; FAM121A antibody; Family with sequence similarity 121A antibody; MGC129748 antibody; Protein FAM121A antibody; UNQ8193 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human MICOS complex subunit MIC27 protein (163-268AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，APOOL Antibody (CSB-PA001949LA01HU)，的标记方式是Non-conjugated。对于APOOL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001949LB01HU APOOL Antibody, HRP conjugated ELISA
    FITC CSB-PA001949LC01HU APOOL Antibody, FITC conjugated
    Biotin CSB-PA001949LD01HU APOOL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function,.
  • 基因功能参考文献：
    1. APOOL is a cardiolipin-binding component of the Mitofilin/MINOS protein complex. PMID: 23704930
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion.
  • 蛋白家族：
    Apolipoprotein O/MICOS complex subunit Mic27 family
  • 数据库链接：

    HGNC: 24009

    OMIM: 300955

    KEGG: hsa:139322

    STRING: 9606.ENSP00000362268

    UniGene: Hs.512181