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APOF Antibody

  • 货号：
    CSB-PA000905
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using ApoF Polyclonal Antibody
    • Western Blot analysis of KB PC-3 MCF7 cells using ApoF Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q13790
  • 基因名：
    APOF
  • 别名：
    Apo-F antibody; Apof antibody; APOF_HUMAN antibody; Apolipoprotein F antibody; DKFZp781G18150 antibody; Lipid transfer inhibitor protein antibody; LTIP antibody; MGC22520 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ApoF.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
  • 基因功能参考文献：
    1. Direct interactions between C/EBPalpha and ETS-1 were important for high liver-specific expression of ApoF. PMID: 25726912
    2. this study has identified apoF as likely another target gene of FXR. PMID: 24211198
    3. LTIP translocation is dependent on LDL lipid composition PMID: 21937674
    4. LTIP tailors CETP-mediated remodeling of HDL3 and HDL2 particles in subclass-specific ways, strongly implicating it as a regulator of HDL metabolism PMID: 12907677
    5. we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males. PMID: 17901467
    6. lipoprotein composition may influence the status of lipid transfer inhibitor protein activity PMID: 18369235

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Apolipoprotein F family
  • 组织特异性：
    Expressed by the liver and secreted in plasma.
  • 数据库链接：

    HGNC: 615

    OMIM: 107760

    KEGG: hsa:319

    STRING: 9606.ENSP00000381250

    UniGene: Hs.534302