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AP3M2 Antibody

  • 货号：
    CSB-PA001878GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P53677
  • 基因名：
    AP3M2
  • 别名：
    AP3M2 antibody; AP-3 complex subunit mu-2 antibody; Adaptor-related protein complex 3 subunit mu-2 antibody; Clathrin assembly protein assembly protein complex 3 mu-2 medium chain antibody; Clathrin coat assembly protein AP47 homolog 2 antibody; Clathrin coat-associated protein AP47 homolog 2 antibody; Golgi adaptor AP-1 47 kDa protein homolog 2 antibody; HA1 47 kDa subunit homolog 2 antibody; Mu3B-adaptin antibody; P47B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human AP3M2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
  • 基因功能参考文献：
    1. some AP3M2 mutations still remain candidates for unmapped disorders including epilepsy, febrile seizure, and other neuronal developmental disorders associated with functional abnormalities of GABAergic transmission PMID: 17293072
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Adaptor complexes medium subunit family
  • 数据库链接：

    HGNC: 570

    OMIM: 610469

    KEGG: hsa:10947

    STRING: 9606.ENSP00000174653

    UniGene: Hs.654529