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AP1B1 Antibody

  • 货号：
    CSB-PA928455
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA928455(AP1B1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using CSB-PA928455(AP1B1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q10567
  • 基因名：
    AP1B1
  • 别名：
    Adaptin; beta 2 (beta) antibody; Adaptor protein complex AP-1 subunit beta-1 antibody; Adaptor related protein complex 1; beta 1 subunit antibody; Adaptor related protein complex 2; beta 1 subunit antibody; Adaptor-related protein complex 1 subunit beta-1 antibody; ADTB1 antibody; ADTB2 antibody; AP 1 complex subunit beta 1 antibody; AP 2 complex subunit beta 1 antibody; AP-1 complex subunit beta-1 antibody; AP1 Beta antibody; AP1B1 antibody; AP1B1_HUMAN antibody; AP2 Beta antibody; AP2B1 antibody; Beta-1-adaptin antibody; Beta-adaptin 1 antibody; Beta1 adaptin antibody; Beta2 adaptin antibody; CLAPB1 antibody; CLAPB2 antibody; Clathrin assembly protein complex 1 beta large chain antibody; Golgi adaptor HA1/AP1 adaptin beta subunit antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human AP1B1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 基因功能参考文献：
    1. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 are capable of carrying out basolateral sorting of ClC-2. PMID: 25739457
    2. AP1B regulates basolateral EGFR membrane delivery predominantly in the biosynthetic route in MDCK cells monolayers. PMID: 23205726
    3. The conclude that in addition to its role in endocytosis, ARH cooperates with AP-1B in basolateral exocytosis of LDLR from recycling endosomes. PMID: 21444685
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • 蛋白家族：
    Adaptor complexes large subunit family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 554

    OMIM: 600157

    KEGG: hsa:162

    STRING: 9606.ENSP00000350199

    UniGene: Hs.368794