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ANGPTL1 Antibody

  • 货号：
    CSB-PA005098
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of mouse heart mouse kidney cells using Angptl1/2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O95841
  • 基因名：
    ANGPTL1
  • 别名：
    ANG 3 antibody; ANG-3 antibody; ANG3 antibody; Angioarrestin antibody; Angiopoietin 3 antibody; Angiopoietin like 1 antibody; Angiopoietin like protein 1 antibody; Angiopoietin related protein 1 antibody; Angiopoietin Y1 antibody; Angiopoietin-3 antibody; Angiopoietin-like protein 1 antibody; Angiopoietin-related protein 1 antibody; ANGL1_HUMAN antibody; ANGPT3 antibody; ANGPTL1 antibody; AngY antibody; ARP1 antibody; dJ595C2.2 antibody; KIAA0351 antibody; UNQ162 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Angptl1/2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Low levels of ANGPTL1 is associated with colorectal cancer metastasis. PMID: 28606130
    2. ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 signaling pathway. PMID: 28904065
    3. Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome. PMID: 26829602
    4. Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis PMID: 25970467
    5. ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG. PMID: 23434592
    6. Inhibits experimental melanoma growth when transfected into murine cells. PMID: 15940350
    7. Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages. PMID: 18182823
    8. Overexpression of angiopoietin 1 and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity. PMID: 18644593

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  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.
  • 数据库链接：

    HGNC: 489

    OMIM: 603874

    KEGG: hsa:9068

    STRING: 9606.ENSP00000234816

    UniGene: Hs.591474