ANAPC4 Antibody
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货号:CSB-PA001699GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q9UJX5
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基因名:
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别名:ANAPC 4 antibody; anapc4 antibody; Anaphase Promoting Complex Subunit 4 antibody; Anaphase-promoting complex subunit 4 antibody; APC 4 antibody; APC Complex Protein CUT20 antibody; APC4 antibody; APC4_HUMAN antibody; CUT20 antibody; Cyclosome subunit 4 antibody; LID1 antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human ANAPC4
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB,IHC
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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基因功能参考文献:
- Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1. PMID: 20686030
- Studies indicate that APC/C(Cdh1) is required to maintain genomic stability. PMID: 19826416
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亚细胞定位:Nucleus.
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蛋白家族:APC4 family
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数据库链接:
HGNC: 19990
OMIM: 606947
KEGG: hsa:29945
STRING: 9606.ENSP00000318775
UniGene: Hs.152173
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