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AMY2A Antibody

  • 货号：
    CSB-PA001689ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Pancreatic alpha-amylase antibody at 6μg/ml + Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 58, 31 kDa
      Observed band size: 58 kDa
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA001689ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001689ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) AMY2A Polyclonal antibody
  • Uniprot No.：
    P04746
  • 基因名：
    AMY2A
  • 别名：
    AMY2A antibody; Pancreatic alpha-amylase antibody; PA antibody; EC 3.2.1.1 antibody; 1,4-alpha-D-glucan glucanohydrolase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Pancreatic alpha-amylase protein (242-511AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Data show that serum amylase was found to be correlated with waist circumference, ghrelin and PYY3-36. PMID: 26495778
    2. Data show that amylase-alpha2A autoantibodies may help to diagnosis of autoimmune pancreatitis (AIP) and to differentiate AIP subtypes. PMID: 26335011
    3. Studies indicate that chloride activates alpha-amylases and ACE, and gaining insight into the potential mechanisms by which chloride functions in PSII. PMID: 21366335
    4. Mammalian pancreatic alpha-amylases share a common carbohydrate binding activity and specifically bind to the intestinal brush border. PMID: 22584580
    5. We demonstrated that AMY2A is frequently silenced in gastric carcinoma deletion 1p21.1. PMID: 20428766
    6. A new approach for the discovery and subsequent structural elucidation of oligosaccharide-based inhibitors of alpha-amylases based upon autoglucosylation of known alpha-glucosidase inhibitors is presented. PMID: 15304511
    7. Autoantibody against amylase alpha-2A is a novel diagnostic marker for both autoimmune pancreatitis and fulminant type 1 diabetes. PMID: 19001184

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  • 亚细胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    Glycosyl hydrolase 13 family
  • 组织特异性：
    Detected in pancreas (at protein level).
  • 数据库链接：

    HGNC: 477

    OMIM: 104650

    KEGG: hsa:279

    STRING: 9606.ENSP00000397582

    UniGene: Hs.654437