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AMPD3 Antibody

  • 货号：
    CSB-PA008865
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q01432
  • 基因名：
    AMPD3
  • 别名：
    Adenosine monophosphate deaminase (isoform E) antibody; Adenosine monophosphate deaminase 3 antibody; AMP aminohydrolase antibody; AMP deaminase 3 antibody; AMP deaminase isoform E antibody; Ampd3 antibody; AMPD3_HUMAN antibody; Erythrocyte AMP deaminase antibody; Erythrocyte specific AMP deaminase antibody; Erythrocyte specific protein antibody; Erythrocyte type AMP deaminase antibody; Erythroid Marker antibody; Myoadenylate deaminase antibody; OTTHUMP00000230743 antibody; OTTHUMP00000230746 antibody; OTTHUMP00000230747 antibody; OTTHUMP00000230748 antibody; OTTHUMP00000230749 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human AMPD3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    AMP deaminase plays a critical role in energy metabolism.
  • 基因功能参考文献：
    1. N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding PMID: 12213808
    2. mtDNA deletion coordinately induces AMP deaminase to contribute to the loss of atrial adenine nucleotides through degrading AMP excessively. PMID: 12604357
    3. The primary underlying mechanism for increased catabolic flow through the AMP deaminase reaction in circulating erythrocytes of individuals with familial phosphofructokinase deficiency is Ca2+-calmodulin activation of AMP deaminase isoform E. PMID: 16670071
  • 相关疾病：
    Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
  • 蛋白家族：
    Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
  • 数据库链接：

    HGNC: 470

    OMIM: 102772

    KEGG: hsa:272

    STRING: 9606.ENSP00000379802

    UniGene: Hs.501890