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AKAP2 Antibody

  • 货号：
    CSB-PA010254
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2D5
  • 基因名：
    AKAP2
  • 别名：
    AKAP2 antibody; KIAA0920 antibody; PRKA2A-kinase anchor protein 2 antibody; AKAP-2 antibody; AKAP-KL antibody; Protein kinase A-anchoring protein 2 antibody; PRKA2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human AKAP 2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.
  • 基因功能参考文献：
    1. study of the variants in AKAP2 gene did not support its association with the susceptibility of adolescent idiopathic scoliosis in the Chinese population. PMID: 28838314
    2. expression of AKAP2 was elevated in ovarian cancer. Furthermore, overexpression of AKAP2 promoted the growth and migration of ovarian cancer cells, whereas knockdown of AKAP2 expression reduced the growth and migration of ovarian cancer cells. PMID: 28849175
    3. AKAP2 was therefore implicated as a novel gene mutated in a Chinese family with adolescent idiopathic scoliosis. PMID: 26989089
    4. AKAP2 is expressed in human prostates, its expression is elevated in metastatic prostate cancer. PMID: 26432469
  • 数据库链接：

    HGNC: 372

    OMIM: 604582

    KEGG: hsa:11217

    STRING: 9606.ENSP00000451476

    UniGene: Hs.591908