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ADGRE1 Antibody

  • 货号：
    CSB-PA613493ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA613493ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA 613493ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ADGRE1 Polyclonal antibody
  • Uniprot No.：
    Q14246
  • 基因名：
  • 别名：
    ADGRE1 antibody; Adhesion G protein coupled receptor E1 antibody; Adhesion G protein-coupled receptor E1 antibody; AGRE1_HUMAN antibody; Cell surface glycoprotein EMR1 antibody; Cell surface glycoprotein F4/80 antibody; DD7A5 7 antibody; Egf like module containing mucin like hormone receptor like 1 antibody; Egf like module containing mucin like hormone receptor like sequence 1 antibody; EGF like module receptor 1 antibody; EGF TM7 antibody; EGF-like module receptor 1 antibody; EGF-like module-containing mucin-like hormone receptor-like 1 antibody; EGFTM7 antibody; EMR 1 antibody; EMR1 antibody; EMR1 hormone receptor antibody; Gpf480 antibody; Ly71 antibody; Lymphocyte antigen 71 antibody; TM7LN3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Adhesion G protein-coupled receptor E1 protein (21-290AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
  • 基因功能参考文献：
    1. EMR1 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3. PMID: 20625511
    3. Highly specific marker for eosinophils. PMID: 17823986
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 组织特异性：
    Expression is restricted to eosinophils.
  • 数据库链接：

    HGNC: 3336

    OMIM: 600493

    KEGG: hsa:2015

    STRING: 9606.ENSP00000311545

    UniGene: Hs.2375