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ADCY4 Antibody

  • 货号：
    CSB-PA007982
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using A Cyclase IV Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8NFM4
  • 基因名：
  • 别名：
    AC4 antibody; Adcy4 antibody; ADCY4_HUMAN antibody; Adenylate cyclase 4 antibody; Adenylate cyclase type 4 antibody; Adenylate cyclase type IV antibody; Adenylyl cyclase 4 antibody; Adenylyl cyclase antibody; ATP pyrophosphate lyase 4 antibody; ATP pyrophosphate lyase antibody; ATP pyrophosphate-lyase 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human A Cyclase IV.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
  • 基因功能参考文献：
    1. AC4 and AC2, both isoforms stimulated by Gbetagamma, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors. PMID: 21228062
    2. This paper reports the presence of adenylyl cyclases 2, 3, and 4 in mouse olfactory cilia. PMID: 11055432
    3. The HIV-1 regulatory protein Tat was shown to inhibit the activity of adenylyl cyclase in rat microglial cells. PMID: 11299302
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 组织特异性：
    Detected in the zona glomerulosa and the zona fasciculata in the adrenal gland (at protein level).
  • 数据库链接：

    HGNC: 235

    OMIM: 600292

    KEGG: hsa:196883

    STRING: 9606.ENSP00000312126

    UniGene: Hs.443428