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ADAM2 Antibody

  • 货号：
    CSB-PA236720
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA236720(ADAM2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA236720(ADAM2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, hela cells, Primary antibody: CSB-PA236720(ADAM2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q99965
  • 基因名：
    ADAM2
  • 别名：
    A disintegrin and metalloproteinase domain 2 antibody; ADAM 2 antibody; ADAM metallopeptidase domain 2 antibody; Adam2 antibody; ADAM2_HUMAN antibody; AI323749 antibody; Cancer/testis antigen 15 antibody; CRYN1 antibody; CRYN2 antibody; CT15 antibody; Disintegrin and metalloproteinase domain-containing protein 2 antibody; Fertilin beta antibody; Fertilin subunit beta antibody; Ftnb antibody; PH 30 antibody; PH 30b antibody; PH-30 antibody; PH30 antibody; Ph30 beta antibody; PH30-beta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human ADAM2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
  • 基因功能参考文献：
    1. ADAM2, CALR3 and SAGE1 cancer/testis antigens are not promising targets for immunotherapy of breast and lung cancer. PMID: 26252478
    2. The fertilin beta contributes not only to successful fertilization, but may has an important impact in development of preimplantation embryos. PMID: 18292840
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
  • 数据库链接：

    HGNC: 198

    OMIM: 601533

    KEGG: hsa:2515

    STRING: 9606.ENSP00000265708

    UniGene: Hs.177959