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ACOT4 Antibody

  • 货号：
    CSB-PA000804
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using ACOT4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8N9L9
  • 基因名：
    ACOT4
  • 别名：
    ACOT4 antibody; ACOT4_HUMAN antibody; Acyl-CoA thioesterase 4 antibody; Acyl-coenzyme A thioesterase 4 antibody; Peroxisomal acyl CoA thioesterase 2B antibody; Peroxisomal acyl coenzyme A thioester hydrolase Ib antibody; Peroxisomal long-chain acyl-CoA thioesterase Ib antibody; PTE-2b antibody; PTE-Ib antibody; Pte1b antibody; Pte2b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ACOT4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs.
  • 基因功能参考文献：
    1. Exome sequencing revealed an association with ACOT4 and increased risk of ischemic stroke. PMID: 25961151
    2. ACOT4 and ACOT8 are responsible for the termination of beta-oxidation of dicarboxylic acids of medium-chain length with the concomitant release of the corresponding free acids PMID: 16141203
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    C/M/P thioester hydrolase family
  • 组织特异性：
    Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.
  • 数据库链接：

    HGNC: 19748

    OMIM: 614314

    KEGG: hsa:122970

    STRING: 9606.ENSP00000323071

    UniGene: Hs.49433