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ACAD10 Antibody

  • 货号：
    CSB-PA060187
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q6JQN1
  • 基因名：
    ACAD10
  • 别名：
    ACAD10 antibody; Acyl-CoA dehydrogenase family member 10 antibody; ACAD-10 antibody; EC 1.3.99.- antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ACAD-10.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA.
  • 基因功能参考文献：
    1. Six polymorphisms (rs12229654 at 12q24.1, rs671 of ALDH2, rs11066015 of ACAD10, rs2074356 and rs11066280 of HECTD4, and rs3782886 of BRAP) were found to be associated with both systolic and diastolic blood pressure, with those at 12q24.1 or in ACAD10 or BRAP being novel determinants of blood pressure in Japanese. PMID: 28562329
    2. ACAD10 has significant activity towards the branched-chain substrates R and S, 2 methyl-C15-CoA and is highly expressed in fetal but not adult brain PMID: 21237683
    3. Results propose that ACAD10 variation may increase type 2 diabetes susceptibility by impairing insulin sensitivity via abnormal lipid oxidation. PMID: 20390405
    4. cDNA ACAD10 maps to chromosome 12q24.1 PMID: 15560374
  • 蛋白家族：
    Acyl-CoA dehydrogenase family
  • 组织特异性：
    Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain. Expression levels varying from isoform to isoform.
  • 数据库链接：

    HGNC: 21597

    OMIM: 611181

    KEGG: hsa:80724

    STRING: 9606.ENSP00000389813

    UniGene: Hs.331141