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ACAA2 Antibody

  • 货号：
    CSB-PA297340
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA297340(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA297340(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: NIH/3T3 cells, A172 cells, human liver cancer tissue, Primary antibody: CSB-PA297340(ACAA2 Antibody) at dilution 1/375, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P42765
  • 基因名：
    ACAA2
  • 别名：
    3 ketoacyl CoA thiolase antibody; 3 ketoacyl CoA thiolase mitochondrial antibody; 3-ketoacyl-CoA thiolase, mitochondrial antibody; 3-oxoacyl-CoA thiolase, mitochondrial antibody; ACAA 2 antibody; Acaa2 antibody; Acetyl CoA acyltransferase 2 antibody; Acetyl CoA acyltransferase antibody; Acetyl Coenzyme A acyltransferase 2 antibody; Acetyl-CoA acyltransferase antibody; Beta ketothiolase antibody; Beta-ketothiolase antibody; DSAEC antibody; Mitochondrial 3 oxoacyl CoA thiolase antibody; Mitochondrial 3 oxoacyl Coenzyme A thiolase antibody; Mitochondrial 3-oxoacyl-CoA thiolase antibody; T1 antibody; THIM_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human ACAA2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation. Abolishes BNIP3-mediated apoptosis and mitochondrial damage.
  • 基因功能参考文献：
    1. ACAA2 is a functional BNIP3 binding partner and provide a possible linkage between fatty acid metabolism and apoptosis of cells. PMID: 18371312
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Thiolase family
  • 数据库链接：

    HGNC: 83

    OMIM: 604770

    KEGG: hsa:10449

    STRING: 9606.ENSP00000285093

    UniGene: Hs.200136