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ABHD4 Antibody

  • 货号：
    CSB-PA050000
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q8TB40
  • 基因名：
    ABHD4
  • 别名：
    ABHD4(Lyso)-N-acylphosphatidylethanolamine lipase antibody; EC 3.1.1.- antibody; Alpha/beta hydrolase domain-containing protein 4 antibody; Abhydrolase domain-containing protein 4 antibody; Alpha/beta-hydrolase 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ABHD4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
  • 基因功能参考文献：
    1. ABHD4 is a novel genetic regulator of anoikis sensitivity. PMID: 22488300
    2. Lysophospholipase/phospholipase B (EC 3.1.1.5) specific for N-acyl phosphatidylethanolamine (NAPE) suggesting a role in the biosynthesis of N-acyl ethanolamines including the endocannabinoid anandamide. PMID: 16818490
  • 蛋白家族：
    Peptidase S33 family, ABHD4/ABHD5 subfamily
  • 数据库链接：

    HGNC: 20154

    KEGG: hsa:63874

    STRING: 9606.ENSP00000414558

    UniGene: Hs.445665