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ABHD10 Antibody

  • 货号：
    CSB-PA591994
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ABHD10 Polyclonal antibody
  • Uniprot No.：
    Q9NUJ1
  • 基因名：
    ABHD10
  • 别名：
    Abhd10 antibody; ABHDA_HUMAN antibody; Abhydrolase domain containing 10 antibody; Abhydrolase domain-containing protein 10 antibody; Abhydrolase domain-containing protein 10; mitochondrial antibody; Alpha/beta hydrolase domain containing protein 10 mitochondrial antibody; mitochondrial antibody; Mycophenolic acid acyl glucuronide esterase mitochondrial antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Synthesized peptide derived from human protein . at AA range: 220-300
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB ,ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:5000-20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate.
  • 基因功能参考文献：
    1. Which potently inhibited ABHD10 activity. PMID: 25217485
    2. mitochondrial localization of rat Abhd10 PMID: 21078990
    3. ABHD10 is responsible for deglucuronidation of mycophenolic acid acyl-glucuronide in liver. PMID: 22294686
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    AB hydrolase superfamily
  • 数据库链接：

    HGNC: 25656

    KEGG: hsa:55347

    STRING: 9606.ENSP00000273359

    UniGene: Hs.477115