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A4GNT Antibody

  • 货号:
    CSB-PA001009LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA001009LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001009LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) A4GNT Polyclonal antibody
  • Uniprot No.:
    Q9UNA3
  • 基因名:
    A4GNT
  • 别名:
    4-N-acetylglucosaminyltransferase antibody; A4GCT_HUMAN antibody; A4GNT antibody; Alpha 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Alpha4GnT antibody; EC 2.4.1. antibody; MGC149493 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Alpha-1,4-N-acetylglucosaminyltransferase protein (26-340AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,A4GNT Antibody (CSB-PA001009LA01HU),的标记方式是Non-conjugated。对于A4GNT Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001009LB01HU A4GNT Antibody, HRP conjugated ELISA
    FITC CSB-PA001009LC01HU A4GNT Antibody, FITC conjugated
    Biotin CSB-PA001009LD01HU A4GNT Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas.
  • 基因功能参考文献:
    1. human alpha1,4-N-acetylglucosaminyltransferase (alpha4GnT) is responsible for O-glycan biosynthesis and has a role in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation PMID: 22307328
    2. Up-regulation of alpha-1,4-N-acetylglucosaminyltransferase is associated with pancreatic cancer PMID: 16441422
  • 亚细胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 32 family
  • 组织特异性:
    Detected in stomach and pancreas.
  • 数据库链接:

    HGNC: 17968

    KEGG: hsa:51146

    STRING: 9606.ENSP00000236709

    UniGene: Hs.278960