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中文名称:大鼠促肾上腺皮质激素(ACTH)酶联免疫试剂盒
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货号:CSB-E06875r
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规格:96T/48T
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价格:¥3900/¥2500
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其他:
产品详情
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产品描述:促肾上腺皮质激素(ACTH)是一种多功能的生物激素,可以在人体内引发一系列生理和行为反应。它是由脑垂体中的垂体前叶产生的,并通过血液循环传递到全身各个部位。ACTH有助于促进新陈代谢、影响机体对应激性物反应。j9九游会登录入口首页生物所提供的Rat adrenocorticotropic hormone (ACTH) ELISA kit属于ELISA检测试剂盒,采用竞争法定量检测大鼠血清、血浆、组织匀浆样本中的ACTH,其灵敏度为j9九游会登录入口首页生物所提供的1.25 pg/mL,检测范围为1.25 pg/mL-50 pg/mL。
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缩写:ACTH
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates
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检测范围:1.25 pg/mL-50 pg/mL
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灵敏度:1.25 pg/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Metabolism
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测定原理:quantitative
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测定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<15% Three samples of known concentration were tested in twenty assays to assess. -
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of rat ACTH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 95 Range % 90-99 1:2 Average % 96 Range % 91-102 1:4 Average % 86 Range % 82-94 1:8 Average % 89 Range % 82-96 -
回收率:
The recovery of rat ACTH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 90 86-96 EDTA plasma (n=4) 101 97-105 -
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. pg/ml OD1 OD2 Average 50 0.341 0.340 0.341 25 0.476 0.474 0.475 11.5 0.700 0.713 0.707 3.75 1.056 1.067 1.062 1.25 1.468 1.387 1.428 0 1.945 1.864 1.905 -
数据处理:
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货期:3-5 working days
引用文献
- Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m J Wang,Scientific reports,2023
- Total Saikosaponins Attenuates Depression-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats by Regulating the PI3K/AKT/NF-κB … Z Zhou,Evidence-Based Complementary and Alternative Medicine,2022
- Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway Xiwen Geng,Oxidative Medicine and Cellular Longevity,2021
- Estrogen re-enhanced prenatal stress-related visceral sensitization and pain regulation J Chen,Research Square,2020
- The Involvement of Notch1 Signaling Pathway in Mid-aged Female Rats under Chronic Restraint Stress J Shen,Neuroscience Letters,2020
- Saponin extract of Baihe-Zhimu Tang ameliorates depression in chronic mild stress rats D Jia,Journal of Functional Foods,2020
- Vitamin D3 attenuates anxiety-like behavior in long-term ovariectomized rats with unpredictable mild stress BARANENKO D,BIOCELL,2019
- Metabolomic signatures and microbial community profiling of depressive rat model induced by adrenocorticotrophic hormone Song J, et al,Journal of Translational Medicine,2019
- The Effects of High Peripubertal Caffeine Exposure on the Adrenal Gland in Immature Male and Female Rats Ryu KY,Nutrients,2019
- Chronic paradoxical sleep deprivation-induced depression Ma W, et al,Life Sciences,2019
- Exposure to cell phone radiofrequency changes corticotrophin hormone levels and histology of the brain and adrenal glands in male Wistar rat Sima Shahabi.et al,Iranian Journal of Basic Medical Sciences,2018
- Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes Wei S.et al,BMC Neuroscience,2018
- Transplantation of bone marrow mesenchymal stem cells reduces GluR1 expression in the hippocampus and amygdala and affects secretion of stress-related hormones in rats with spinal cord injuries: a potential anti-chronic stress mechanism Jia-Jia Sun.et al,INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2018
- Perfluorooctane sulfonate (PFOS) can alter the hypothalamic?pituitary?adrenal (HPA) axis activity by modifying CRF1 and glucocorticoid receptors R. Salgado.et al,Toxicology Letters,2018
- Sini Decoction improves adrenal function and the short-term outcome of septic rats through downregulation of adrenal Toll-like receptor 4 expression Fang Lai.et al,/,2018
- A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats Le Zhao.et al, RSC Adv,2018
- Assessment of the role of intracranial hypertension and stress on hippocampal cell apoptosis and hypothalamic-pituitary dysfunction after TBI Tan H.et al,Sci Rep,2017
- Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency. Zhang Y.et al,J Surg Res.,2015
- High-Cholesterol Diet Disrupts the Levels of Hormones Derived from Anterior Pituitary Basophilic Cells Yang J.et al,J Neuroendocrinol.,2016
- Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic-pituitary-adrenal axis in adult male rats Pereiro N et al,Toxicol Lett,2014
- Effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on serum hormone levels in rats Jin YB et al,J Radiat Res,2012
相关产品
靶点详情
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最新研究进展:促肾上腺皮质激素(ACTH)是由下丘脑-垂体-肾上腺(HPA)轴分泌的激素,对于调节肾上腺皮质激素的合成和分泌具有重要作用。以下是最近一些关于ACTH的研究进展:ACTH在应激反应中的作用:ACTH参与了应激反应的调节。最近的研究表明,应激可以影响下丘脑的神经元活动,导致ACTH的分泌增加。而ACTH又可以刺激肾上腺皮质激素的合成和分泌,从而调节机体的应激反应。因此,ACTH也被广泛应用于应激相关疾病的治疗。ACTH在自身免疫性皮肤病中的作用:ACTH具有抗炎作用,已被广泛用于治疗自身免疫性皮肤病,如银屑病和天疱疮等。最近的研究表明,ACTH治疗不仅可以减轻症状,还可以改善患者的生活质量。ACTH在儿童癫痫中的应用:ACTH在儿童癫痫治疗中也有广泛应用。最近的研究表明,ACTH治疗可以显著降低癫痫持续时间和频率,同时改善儿童的认知和行为表现。ACTH在肾上腺皮质功能不足症中的应用:ACTH也被用于治疗肾上腺皮质功能不足症,如原发性肾上腺皮质功能不足和副肾上腺皮质功能不足等。最近的研究表明,ACTH治疗可以有效改善患者的症状和生活质量。
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