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  4. Human T-complex protein 1 subunit epsilon(CCT5) ELISA kit

Human T-complex protein 1 subunit epsilon(CCT5) ELISA kit

  • 中文名称：
    人T复合物蛋白1亚基ε(CCT5)酶联免疫试剂盒
  • 货号：
    CSB-EL004862HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human CCT5 ELISA Kit was designed for the quantitative measurement of Human CCT5 protein in serum, plasma,tissue homogenates, cell lysates. It is a Sandwich ELISA kit, its detection range is 15.6 pg/mL-1000 pg/mL and the sensitivity is 3.9 pg/mL.

  • 别名：
    CCT 5 ELISA Kit; CCT epsilon ELISA Kit; CCT-epsilon ELISA Kit; CCT5 ELISA Kit; CCTE ELISA Kit; CCTepsilon ELISA Kit; Chaperonin containing T-complex polypeptide 1; subunit 5 ELISA Kit; Chaperonin containing TCP 1 epsilon ELISA Kit; Chaperonin containing TCP 1 subunit 5 ELISA Kit; Chaperonin containing TCP 1 subunit 5 epsilon ELISA Kit; Chaperonin containing TCP1 epsilon ELISA Kit; Chaperonin containing TCP1 subunit 5 ELISA Kit; Chaperonin containing TCP1 subunit 5 epsilon ELISA Kit; KIAA0098 ELISA Kit; T complex protein 1 epsilon subunit ELISA Kit; T complex protein 1 subunit epsilon ELISA Kit; T-complex protein 1 subunit epsilon ELISA Kit; TCP 1 epsilon ELISA Kit; TCP-1-epsilon ELISA Kit; TCP1epsilon ELISA Kit; TCPE ELISA Kit; TCPE_HUMAN ELISA Kit
  • 缩写：
    CCT5
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma,tissue homogenates, cell lysates
  • 检测范围：
    15.6 pg/mL-1000 pg/mL
  • 灵敏度：
    3.9 pg/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Signal Transduction
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
  • 基因功能参考文献：
    1. CCT5 complex caps mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC chaperonin and the CCT5 complex PMID: 25995452
    2. H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5. PMID: 25124038
    3. introduction of the truncated human CCT epsilon subunit into yeast cells PMID: 22232265
    4. A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia. PMID: 16399879
  • 相关疾病：
    Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive (HSNSP)
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族：
    TCP-1 chaperonin family
  • 数据库链接：

    HGNC: 1618

    OMIM: 256840

    KEGG: hsa:22948

    STRING: 9606.ENSP00000280326

    UniGene: Hs.1600