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Human Serum amyloid A-4 protein(SAA4) ELISA kit

  • 中文名称:
    人血清淀粉样蛋白A4(SAA4)酶联免疫试剂盒
  • 货号:
    CSB-EL020659HU
  • 规格:
    96T/48T
  • 价格:
    ¥3600/¥2500
  • 其他:

产品详情

  • 产品描述:
        SAA4 (Serum amyloid A4) 是一种由SAA4基因编码的蛋白质,属于血清淀粉样蛋白A(SAA)家族。SAA4的主要功能是作为一种炎症蛋白参与炎症反应的调节。SAA4可以在肝脏和其他组织中被产生,其产生水平会受到多种因素的影响,如感染、肿瘤、创伤、糖尿病等。研究表明,SAA4在多种疾病的诊断和治疗中可能具有潜在的临床应用价值。
        j9九游会登录入口首页生物所提供的Human Serum amyloid A-4 protein(SAA4) ELISA kit属于ELISA检测试剂盒,采用双抗夹心法定量检测人血清、血浆、组织匀浆样本中的SAA4,其灵敏度为3.9 ng/ml,检测范围为15.6 ng/ml-1000 ng/ml。
     
  • 别名:
    Amyloid A; serum; 4 ELISA Kit; C SAA ELISA Kit; C-SAA ELISA Kit; Constitutively expressed serum amyloid A protein ELISA Kit; CSAA ELISA Kit; SAA 4 ELISA Kit; Saa4 ELISA Kit; SAA4 protein ELISA Kit; SAA4_HUMAN ELISA Kit; Serum amyloid A 4 protein ELISA Kit; Serum amyloid A-4 protein ELISA Kit; Serum amyloid A4 constitutive ELISA Kit
  • 缩写:
    SAA4
  • Uniprot No.:
  • 种属:
    Homo sapiens (Human)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    15.6 ng/ml-1000 ng/ml.
  • 灵敏度:
    3.9 ng/ml.
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Cardiovascular
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 最新研究进展:
    SAA4(serum amyloid A4)是SAA蛋白家族的一员,参与机体的免疫调节和炎症反应。最新研究表明,SAA4在某些肿瘤中表达升高,与肿瘤的发生和进展密切相关。此外,SAA4也参与了许多炎症和自身免疫疾病的发生和发展,成为新型治疗策略的热点研究对象。
  • 功能:
    Major acute phase reactant.
  • 基因功能参考文献:
    1. Data identified SAA4 as a protein that was positively correlated with RF and RA. SAA4 may represent a novel prescreening marker for the diagnosis of RA. PMID: 28505104
    2. expressed in invasive trophoblast cells PMID: 24951172
    3. Six apolipoproteins (APOA1, APOA2, APOB, APOC2, APOC3, and APOE) were able to differentiate bladder cancer from hernia. SAA4 was significantly increased in bladder cancer subgroups, whereas ProEGF was significantly decreased in bladder cancer subgroups. PMID: 23631828
    4. studies provide the first evidence for a novel type of AA amyloidosis in which the fibrils were formed from a mutated SAA4 protein PMID: 20536400
    5. The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5'-flanking regions were determined. PMID: 12410800

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  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    SAA family
  • 组织特异性:
    Expressed by the liver; secreted in plasma.
  • 数据库链接:

    HGNC: 10516

    OMIM: 104752

    KEGG: hsa:6291

    STRING: 9606.ENSP00000278222

    UniGene: Hs.1955