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  4. Recombinant Human Serum amyloid A-4 protein (SAA4)

Recombinant Human Serum amyloid A-4 protein (SAA4)

  • 中文名称：
    人SAA4重组蛋白
  • 货号：
    CSB-YP020659HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SAA4重组蛋白
  • 货号：
    CSB-EP020659HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SAA4重组蛋白
  • 货号：
    CSB-EP020659HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SAA4重组蛋白
  • 货号：
    CSB-BP020659HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SAA4重组蛋白
  • 货号：
    CSB-MP020659HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SAA4
  • Uniprot No.：
  • 别名：
    Amyloid A; serum; 4; C SAA; C-SAA; Constitutively expressed serum amyloid A protein; CSAA; SAA 4; Saa4; SAA4 protein; SAA4_HUMAN; Serum amyloid A 4 protein; Serum amyloid A-4 protein; Serum amyloid A4 constitutive
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    19-130
  • 氨基酸序列
    ES WRSFFKEALQ GVGDMGRAYW DIMISNHQNS NRYLYARGNY DAAQRGPGGV WAAKLISRSR VYLQGLIDCY LFGNSSTVLE DSKSNEKAEE WGRSGKDPDR FRPDGLPKKY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Major acute phase reactant.
  • 基因功能参考文献：
    1. Data identified SAA4 as a protein that was positively correlated with RF and RA. SAA4 may represent a novel prescreening marker for the diagnosis of RA. PMID: 28505104
    2. expressed in invasive trophoblast cells PMID: 24951172
    3. Six apolipoproteins (APOA1, APOA2, APOB, APOC2, APOC3, and APOE) were able to differentiate bladder cancer from hernia. SAA4 was significantly increased in bladder cancer subgroups, whereas ProEGF was significantly decreased in bladder cancer subgroups. PMID: 23631828
    4. studies provide the first evidence for a novel type of AA amyloidosis in which the fibrils were formed from a mutated SAA4 protein PMID: 20536400
    5. The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5'-flanking regions were determined. PMID: 12410800

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    SAA family
  • 组织特异性：
    Expressed by the liver; secreted in plasma.
  • 数据库链接：

    HGNC: 10516

    OMIM: 104752

    KEGG: hsa:6291

    STRING: 9606.ENSP00000278222

    UniGene: Hs.1955