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  4. Human Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit

Human Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit

  • 中文名称：
    人补体C1q肿瘤坏死因子相关蛋白6(C1QTNF6)酶联免疫试剂盒
  • 货号：
    CSB-EL003651HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human C1QTNF6 ELISA Kit was designed for the quantitative measurement of Human C1QTNF6 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 0.312 ng/mL-20 ng/mL and the sensitivity is 0.078 ng/mL.

  • 别名：
    C1q and tumor necrosis factor related protein 6 ELISA Kit; C1QT6_HUMAN ELISA Kit; C1qtnf6 ELISA Kit; Complement C1q tumor necrosis factor related protein 6 ELISA Kit; Complement C1q tumor necrosis factor-related protein 6 ELISA Kit; CTRP 6 ELISA Kit; CTRP6 ELISA Kit; OTTHUMP00000197772 ELISA Kit; OTTHUMP00000197774 ELISA Kit; PRO1151 ELISA Kit; UNQ581 ELISA Kit; ZACRP6 ELISA Kit
  • 缩写：
    C1QTNF6
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.312 ng/mL-20 ng/mL
  • 灵敏度：
    0.078 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Others
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human C1QTNF6 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %97
    Range %92-101
    1:2Average %105
    Range %99-108
    1:4Average %90
    Range %84-94
    1:8Average %87
    Range %82-91
  • 回收率：
    The recovery of human C1QTNF6 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9285-96
    EDTA plasma (n=4)9082-93
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    202.778 2.662 2.720 2.600
    101.926 1.905 1.916 1.796
    51.315 1.342 1.329 1.209
    2.50.703 0.734 0.719 0.599
    1.250.390 0.381 0.386 0.266
    0.6250.295 0.288 0.292 0.172
    0.3120.203 0.209 0.206 0.086
    00.119 0.121 0.120
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 基因功能参考文献：
    1. The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. PMID: 28726640
    2. We found both the rs229527 allele within C1QTNF6 (odds ratio [OR] = 1.23, confidence interval [95% CI]: 1.12-1.33, pAllelic = 4.60 . 10-6) and the rs2284038 allele within RAC2 (OR = 1.10, 95% CI: 1.01-0.19, pAllelic = 3.00 . 10-2) showed significant associations with Graves' Disease susceptibility. PMID: 28665696
    3. CTRP6 expression was decreased in scar tissues and TGF-beta1-treated dermal fibroblasts. CTRP6 inhibits TGF-beta1-induced the proliferation of dermal fibroblasts. PMID: 27155158
    4. CTRP6 inhibits the proliferation and migration of ovarian cancer cells via blocking IL-8/VEGF pathway. PMID: 26648301
    5. CTRP6 is expressed in human synoviocytes, and CTRP6 levels are increased in RA patients. PMID: 26404464
    6. C1qTNF6 is overexpressed and possibly contributes to tumor angiogenesis by activating the Akt pathway in many hepatocellular carcinomas. PMID: 21508531

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  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    HGNC: 14343

    OMIM: 614910

    KEGG: hsa:114904

    STRING: 9606.ENSP00000338812

    UniGene: Hs.22011