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spopl

Speckle-type POZ protein-like is a protein in humans that is encoded by SPOPL gene. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.

spopl Antibodies

spopl for Homo sapiens (Human)

spopl Proteins

spopl Proteins for Homo sapiens (Human)

spopl Proteins for Xenopus laevis (African clawed frog)

spopl Proteins for Mus musculus (Mouse)