npm1

NPM1，即核磷酸蛋白1，别名B23、Numatrin。它是一种主要定位于细胞核仁中的多功能伴侣蛋白，在细胞核和细胞质之间穿梭，参与细胞核糖体合成、中心体复制、DNA修复等过程。NPM1还与P53、ARF等蛋白共同调控细胞凋亡。其作用机制涉及与多种蛋白质相互作用，影响细胞周期调控、细胞增殖、分化和凋亡。NPM1在多种恶性肿瘤细胞中高表达，如急性髓系白血病（AML），其突变形式与疾病的发病机制相关，可作为微小残留病（MRD）监测的重要指标。NPM1的异常表达或功能失调与肿瘤的发生发展密切相关，是研究和治疗急性白血病等恶性肿瘤的关键靶点。

热销产品

Recombinant Human Nucleophosmin (NPM1) (CSB-EP015996HU)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NPM1 Antibody (CSB-PA003492)

验证数据

Western Blot analysis of COS7 cells using Nucleophosmin Polyclonal Antibody

Western Blot analysis of 293 AD293 cells using Nucleophosmin Polyclonal Antibody

Human Nucleophosmin(NPM1) ELISA kit (CSB-EL015996HU)

验证数据

货号：CSB-EL015996HU

规格：96T/48T

灵敏度：5.8 pg/mL

检测范围：23.5 pg/mL-1500 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

npm1 Antibody

npm1 Protein

npm1 ELISA Kit

npm1 Antibodies

npm1 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA015996GA01HU	NPM1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA582765	Phospho-NPM1 (Thr199) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA003471	NPM1 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA003492	NPM1 Antibody	Human,Mouse,Rat,Monkey	WB, IHC, ELISA
CSB-PA020150	Phospho-NPM1 (T234) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA020151	Phospho-NPM1 (T199) Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA020152	NPM1 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA

npm1 Proteins

npm1 Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP015996RA CSB-EP015996RA CSB-BP015996RA CSB-MP015996RA CSB-EP015996RA-B	Recombinant Rat Nucleophosmin (Npm1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

npm1 Proteins for Gallus gallus (Chicken)

产品货号	产品名称	来源
CSB-YP015996CH CSB-EP015996CH CSB-BP015996CH CSB-MP015996CH CSB-EP015996CH-B	Recombinant Chicken Nucleophosmin (NPM1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

npm1 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP015996HU CSB-BP015996HU CSB-MP015996HU CSB-EP015996HU-B	Recombinant Human Nucleophosmin (NPM1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP015996HU	Recombinant Human Nucleophosmin (NPM1)	E.coli

npm1 Proteins for Xenopus laevis (African clawed frog)

产品货号	产品名称	来源
CSB-YP015996XBE CSB-EP015996XBE CSB-BP015996XBE CSB-MP015996XBE CSB-EP015996XBE-B	Recombinant Xenopus laevis Nucleophosmin (npm1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

npm1 Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP663615BO CSB-EP663615BO CSB-BP663615BO CSB-MP663615BO CSB-EP663615BO-B	Recombinant Bovine Nucleophosmin (NPM1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

npm1 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP737048MO CSB-BP737048MO CSB-MP737048MO CSB-EP737048MO-B	Recombinant Mouse Nucleophosmin (Npm1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP737048MO	Recombinant Mouse Nucleophosmin (Npm1)	E.coli