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chmp1b

Charged multivesicular body protein 1b is a protein in humans that is encoded by CHMP1B gene. Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.

chmp1b Antibodies

chmp1b for Homo sapiens (Human)

chmp1b Proteins

chmp1b Proteins for Bos taurus (Bovine)

chmp1b Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

chmp1b Proteins for Gallus gallus (Chicken)

chmp1b Proteins for Xenopus laevis (African clawed frog)

chmp1b Proteins for Homo sapiens (Human)

chmp1b Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)