Vamp2
VAMP2，即囊泡相关膜蛋白2，别名synaptobrevin-2。它是一种在神经递质释放过程中起关键作用的蛋白质，主要在神经系统特异表达。VAMP2作为可溶性细胞膜的关键成分之一，参与形成SNARE（可溶性细胞膜因子附着蛋白受体）复合体，与syntaxin-1A和SNAP-25结合产生诱导融合孔形成的力量，从而介导突触小泡的融合和神经递质的释放。VAMP2在生物学上的意义非常重大，它不仅参与神经递质的正常释放，影响神经系统的信号传递，还与多种神经退行性疾病和精神疾病的发生发展有关。VAMP2的活性受到多种因素的精细调控，包括蛋白质、脂质、代谢离子等。研究表明，VAMP2在不同区域的突触小泡膜上展现出不同的构象，胆固醇丰富的微域对其构象和SNARE组装有重要影响。此外，VAMP2的膜结合特性和活性状态在突触前细胞质中受到严格调控，这对于神经递质释放的时空精度至关重要。
热销产品
Recombinant Human Vesicle-associated membrane protein 2 (VAMP2) (CSB-EP025781HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP025781HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) VAMP2.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP025781HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) VAMP2.
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA055935(VAMP2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA055935(VAMP2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 12%SDS-PAGE,Lysate: 40 μg,Lane 1-3: Human fetal brain tissue, Mouse brain tissue, Hela cells,Primary antibody: CSB-PA055935(VAMP2 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds
Vamp2 Antibodies
Vamp2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA025781GA01HU | VAMP2 Antibody | Human,Mouse,Rat | ELISA |
| CSB-PA025781ESR2HU | VAMP2 Antibody | Human | ELISA, IHC |
Vamp2 Proteins
Vamp2 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025781BO1 CSB-EP025781BO1 CSB-BP025781BO1 CSB-MP025781BO1 CSB-EP025781BO1-B |
Recombinant Bovine Vesicle-associated membrane protein 2 (VAMP2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025781BO | Recombinant Bovine Vesicle-associated membrane protein 2 (VAMP2) | in vitro E.coli expression system |
Vamp2 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025781RA1 CSB-BP025781RA1 CSB-MP025781RA1 CSB-EP025781RA1-B |
Recombinant Rat Vesicle-associated membrane protein 2 (Vamp2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025781RA | Recombinant Rat Vesicle-associated membrane protein 2 (Vamp2) | in vitro E.coli expression system |
| CSB-EP025781RA1 | Recombinant Rat Vesicle-associated membrane protein 2 (Vamp2), partial | E.coli |
Vamp2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025781MO1 CSB-EP025781MO1 CSB-BP025781MO1 CSB-MP025781MO1 CSB-EP025781MO1-B |
Recombinant Mouse Vesicle-associated membrane protein 2 (Vamp2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025781MO | Recombinant Mouse Vesicle-associated membrane protein 2 (Vamp2) | in vitro E.coli expression system |
Vamp2 Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025781XBE1 CSB-EP025781XBE1 CSB-BP025781XBE1 CSB-MP025781XBE1 CSB-EP025781XBE1-B |
Recombinant Xenopus laevis Vesicle-associated membrane protein 2 (vamp2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF025781XBE | Recombinant Xenopus laevis Vesicle-associated membrane protein 2 (vamp2) | in vitro E.coli expression system |
Vamp2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025781HU CSB-BP025781HU CSB-MP025781HU CSB-EP025781HU-B |
Recombinant Human Vesicle-associated membrane protein 2 (VAMP2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP025781HU | Recombinant Human Vesicle-associated membrane protein 2 (VAMP2) | E.coli |
| CSB-CF025781HU | Recombinant Human Vesicle-associated membrane protein 2 (VAMP2) | in vitro E.coli expression system |
Vamp2 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP889016MOW CSB-EP889016MOW CSB-BP889016MOW CSB-MP889016MOW CSB-EP889016MOW-B |
Recombinant Macaca mulatta Vesicle-associated membrane protein 2 (VAMP2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
