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VPS39

VPS39 is a protein in humans that is encoded by VPS39 gene. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.

VPS39 Antibodies

VPS39 for Homo sapiens (Human)

VPS39 Proteins

VPS39 Proteins for Homo sapiens (Human)

VPS39 Proteins for Mus musculus (Mouse)