VDR
VDR，即维生素D受体，别名Vitamin D nuclear receptor variant 1、Vitamin D receptor、Vitamin D3 receptor，它在人体中广泛分布，包括肠道、肾脏、骨骼、血液淋巴系统、泌尿生殖系统以及神经系统等。VDR的作用机制主要是通过与配体1,25-二羟维生素D3结合，形成激素-受体复合物，作用于靶基因上的特定DNA序列，调节基因的表达。VDR在维持机体钙磷代谢、调节细胞增殖和分化等方面发挥重要作用。此外，VDR还参与免疫调节、抗炎、抗感染和肿瘤预防等生理过程。在中枢神经系统中，VDR通过调节神经干细胞的增殖分化、神经营养因子的表达、抗氧化损伤、调节神经递质合成、免疫调节以及抗炎等方面发挥重要作用，与多种神经系统疾病的发生和发展密切相关。
热销产品
VDR Recombinant Monoclonal Antibody (CSB-RA945260A0HU)
验证数据
Western Blot
Positive WB detected in: MCF-7 whole cell lysate, THP-1 whole cell lysate, HL-60 whole cell lysate
All lanes: Vitamin D antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 49, 54 kDa
Observed band size: 49 kDa
IHC image of CSB-RA945260A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Human Vitamin D Receptor,VD R ELISA Kit (CSB-E05136h)
验证数据
货号：CSB-E05136h
规格：96T/48T
灵敏度：1.56 pg/mL
检测范围：6.25 pg/mL-400 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
VDR Antibodies
VDR for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA995273 | Phospho-VDR (Ser208) Antibody | Human | ELISA,WB |
| CSB-PA594723 | VDR (Ab-51) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA160201 | Phospho-VDR (Ser51) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004443 | VDR Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA060061 | Phospho-VDR (S51) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA060062 | Phospho-VDR (S208) Antibody | Human | WB, IF, ELISA |
| CSB-PA060063 | VDR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-RA945260A0HU | VDR Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC |
VDR Proteins
VDR Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP025832HU CSB-EP025832HU CSB-BP025832HU CSB-MP025832HU CSB-EP025832HU-B |
Recombinant Human Vitamin D3 receptor (VDR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VDR ELISA Kit
VDR ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E05136h | Human Vitamin D Receptor,VD R ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 1.56 pg/mL |
