Your Good Partner in Biology Research

USP21

Ubiquitin carboxyl-terminal hydrolase 21 is a protein in humans that is encoded by USP21 gene. Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.

USP21 Proteins

USP21 Proteins for Rattus norvegicus (Rat)

USP21 Proteins for Bos taurus (Bovine)

USP21 Proteins for Mus musculus (Mouse)

USP21 Proteins for Homo sapiens (Human)