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Tnfrsf4

TNFRSF4,即肿瘤坏死因子受体超家族成员4,也被称作CD137或OX40。它是一种主要在活化的T细胞表面表达的共刺激分子。TNFRSF4的作用机制涉及与其配体TNFSF4(也称为OX40L)的结合,这种结合增强了T细胞的存活、增殖和分化,对维持T细胞介导的免疫应答至关重要。TNFRSF4的激活可以促进Th1和Th17细胞的分化,同时抑制调节性T细胞的功能,从而在慢性感染和肿瘤免疫中发挥积极作用。TNFRSF4是调节免疫应答和促进细胞介导的免疫反应的关键分子,其在自身免疫疾病和肿瘤治疗中具有潜在的治疗价值。

热销产品

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (CSB-MP023981HU1)

验证数据

CSB-MP023981HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TNFRSF4 Antibody (CSB-PA006263)

验证数据

CSB-PA006263

Western Blot analysis of PC-12 cells using Ox40 Polyclonal Antibody

Tnfrsf4 Antibodies

Tnfrsf4 for Homo sapiens (Human)

Tnfrsf4 for Mus musculus (Mouse)

Tnfrsf4 Proteins

Tnfrsf4 Proteins for Rattus norvegicus (Rat)

Tnfrsf4 Proteins for Homo sapiens (Human)

Tnfrsf4 Proteins for Mus musculus (Mouse)