TFRC
TFRC,全名为Transferrin Receptor Protein 1,是一种转铁蛋白受体蛋白。它位于细胞膜上,主要负责调节细胞对铁元素的摄取。它通过结合游离铁元素,利用循环将其传送到细胞和组织中。一旦转铁蛋白与游离铁元素结合形成转铁蛋白复合物,它将与细胞表面的TFRC结合。TFRC的主要功能是通过内吞作用将转铁蛋白复合物带入细胞内,以满足细胞对铁元素的需求,从而维持细胞的生长和代谢。 由于TFRC在细胞生长和分化中发挥着重要作用,一些药物输送系统利用TFRC在细胞膜上的表达来提供治疗药物,以增强药物的细胞内输送和靶向效果。因此成为了药物传递和治疗靶点的潜在目标。
更多相关阅读:转铁蛋白受体TFR1(TFRC):铁稳态关键成员,贫血、神经退行性疾病、癌症新锐靶点!
热销产品
● Recombinant Human Transferrin receptor protein 1(TFRC),partial (Active) CSB-MP3648HU
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC at 2μg/mL can bind Anti-TFRC recombinant antibody (CSB-RA023441MA1HU), the EC50 is 3.305-8.220 ng/mL.
● TFRC Recombinant Monoclonal Antibody CSB-RA023441MA1HU
验证数据
The Binding Activity of Human TFRC with Anti-TFRC Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC (CSB-MP3648HU) at 2 μg/mL can bind Anti-TFRC recombinant antibody , the EC50 is 3.305-8.220 ng/mL
TFRC Antibodies
TFRC for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA023441GA01HU | TFRC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA07219B0Rb | TFRC Antibody, HRP conjugated | Human | ELISA |
CSB-PA07219D0Rb | TFRC Antibody, Biotin conjugated | Human | ELISA |
CSB-PA07219A0Rb | TFRC Antibody | Human | ELISA, IHC, IF |
CSB-PA001477 | TFRC Antibody | Human,Mouse | WB, IHC, ELISA |
CSB-PA005607 | TFRC Antibody | Human | WB, ELISA |
CSB-PA010092 | Phospho-TFRC (S24) Antibody | Human,Mouse | WB, IHC, ELISA |
CSB-PA104885 | TFRC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA834425 | TFRC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-RA023441MA1HU | TFRC Recombinant Monoclonal Antibody | Human | ELISA |
TFRC Proteins
TFRC Proteins for Equus caballus (Horse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP651210HO CSB-EP651210HO CSB-BP651210HO CSB-MP651210HO CSB-EP651210HO-B |
Recombinant Horse Transferrin receptor protein 1 (TFRC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Pongo abelii (Sumatran orangutan)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP719275PYX CSB-EP719275PYX CSB-BP719275PYX CSB-MP719275PYX CSB-EP719275PYX-B |
Recombinant Pongo abelii Transferrin receptor protein 1 (TFRC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP726792MO CSB-BP726792MO CSB-MP726792MO CSB-EP726792MO-B |
Recombinant Mouse Transferrin receptor protein 1 (Tfrc), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP816838PI CSB-BP816838PI CSB-MP816838PI CSB-EP816838PI-B |
Recombinant Pig Transferrin receptor protein 1 (TFRC), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Gallus gallus (Chicken)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP856194CH CSB-EP856194CH CSB-BP856194CH CSB-MP856194CH CSB-EP856194CH-B |
Recombinant Chicken Transferrin receptor protein 1 (TFRC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP858708RA1 CSB-BP858708RA1 CSB-MP858708RA1 CSB-EP858708RA1-B |
Recombinant Rat Transferrin receptor protein 1 (Tfrc), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP867082DO CSB-EP867082DO CSB-BP867082DO CSB-MP867082DO CSB-EP867082DO-B |
Recombinant Dog Transferrin receptor protein 1 (TFRC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Felis catus (Cat) (Felis silvestris catus)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP882000CA CSB-EP882000CA CSB-BP882000CA CSB-MP882000CA CSB-EP882000CA-B |
Recombinant Cat Transferrin receptor protein 1 (TFRC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFRC Proteins for Mus musculus(Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-EP726792MO | Recombinant Mouse Transferrin receptor protein 1 (Tfrc), partial | E.coli |
TFRC Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-MP3648HU | Recombinant Human Transferrin receptor protein 1 (TFRC), partial (Active) | Mammalian cell |
TFRC ELISA Kit
TFRC ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E08389m | Mouse transferrin receptor,TFR ELISA Kit | serum, plasma, tissue homogenates | 0.156 ng/mL |
TFRC ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E09100h | Human soluble transferrin receptor,sTfR ELISA Kit | serum, plasma | Request Information |