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TFRC

TFRC,全名为Transferrin Receptor Protein 1,是一种转铁蛋白受体蛋白。它位于细胞膜上,主要负责调节细胞对铁元素的摄取。它通过结合游离铁元素,利用循环将其传送到细胞和组织中。一旦转铁蛋白与游离铁元素结合形成转铁蛋白复合物,它将与细胞表面的TFRC结合。TFRC的主要功能是通过内吞作用将转铁蛋白复合物带入细胞内,以满足细胞对铁元素的需求,从而维持细胞的生长和代谢。 由于TFRC在细胞生长和分化中发挥着重要作用,一些药物输送系统利用TFRC在细胞膜上的表达来提供治疗药物,以增强药物的细胞内输送和靶向效果。因此成为了药物传递和治疗靶点的潜在目标。

更多相关阅读:转铁蛋白受体TFR1(TFRC):铁稳态关键成员,贫血、神经退行性疾病、癌症新锐靶点!

热销产品

Recombinant Human Transferrin receptor protein 1(TFRC),partial (Active) CSB-MP3648HU

验证数据

High Purity Validated by SDS-PAGE
CSB-MP3648HU SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA
CSB-MP3648HU AC

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC at 2μg/mL can bind Anti-TFRC recombinant antibody (CSB-RA023441MA1HU), the EC50 is 3.305-8.220 ng/mL.

TFRC Recombinant Monoclonal Antibody CSB-RA023441MA1HU

验证数据

ELISA
CSB-RA023441MA1HU ELISA

The Binding Activity of Human TFRC with Anti-TFRC Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC (CSB-MP3648HU) at 2 μg/mL can bind Anti-TFRC recombinant antibody , the EC50 is 3.305-8.220 ng/mL

TFRC Antibodies

TFRC for Homo sapiens (Human)

TFRC Proteins

TFRC Proteins for Equus caballus (Horse)

TFRC Proteins for Pongo abelii (Sumatran orangutan)

TFRC Proteins for Mus musculus (Mouse)

TFRC Proteins for Sus scrofa (Pig)

TFRC Proteins for Gallus gallus (Chicken)

TFRC Proteins for Rattus norvegicus (Rat)

TFRC Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

TFRC Proteins for Felis catus (Cat) (Felis silvestris catus)

TFRC Proteins for Mus musculus(Mouse)

TFRC Proteins for Homo sapiens (Human)

TFRC ELISA Kit

TFRC ELISA Kit for Mus musculus (Mouse)

TFRC ELISA Kit for Homo sapiens (Human)