TERT

TERT，即端粒酶反转录酶，是端粒酶的核心亚基，由多个结构域组成，包括端粒酶保守基序结构域、催化域和RNA结合域等。它负责在细胞分裂过程中，通过反转录机制将RNA模板转录成DNA，并添加到染色体末端的端粒DNA序列中，从而维持端粒长度，确保细胞的持续增殖能力。TERT的表达受到严格调控，但在肿瘤细胞中常异常上调，与肿瘤的发生和发展密切相关。除了维持端粒长度，TERT还参与DNA修复、细胞存活、防止凋亡、促进生长和增殖等过程，并展现出独立于端粒的新生物学功能，如基因转录调控、血管新生和免疫炎症等。这些发现不仅为理解TERT的生物学作用提供了新的视角，也为治疗端粒酶相关疾病提供了重要的理论基础和潜在的治疗策略。

热销产品

Recombinant Human Telomerase reverse transcriptase (TERT), partial (CSB-EP023391HU)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TERT Antibody

TERT Protein

TERT ELISA Kit

TERT Antibodies

TERT for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA10669A0Rb	TERT Antibody	Human	ELISA, IHC
CSB-PA10669C0Rb	TERT Antibody, FITC conjugated	Human
CSB-PA10669B0Rb	TERT Antibody, HRP conjugated	Human	ELISA
CSB-PA10669D0Rb	TERT Antibody, Biotin conjugated	Human	ELISA
CSB-PA004257	TERT Antibody	Human	WB, IF, ELISA
CSB-PA006014	TERT Antibody	Human	WB, ELISA
CSB-PA050241	Phospho-TERT (S824) Antibody	Human	WB, IHC, ELISA
CSB-PA050242	Phospho-TERT (S227) Antibody	Human	IF, ELISA
CSB-PA912041	TERT Antibody	Human	ELISA,WB,IHC
CSB-PA199893	TERT Antibody	Human	ELISA,WB
CSB-PA257364	TERT Antibody	Human	ELISA,IHC
CSB-PA585649	TERT Antibody	Human	ELISA,IHC
CSB-PA232517	TERT Antibody	Human	WB, IHC, ELISA
CSB-RA798840A0HU	TERT Recombinant Monoclonal Antibody	Human	ELISA, IHC

TERT Proteins

TERT Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP023391HU CSB-BP023391HU CSB-MP023391HU CSB-EP023391HU-B	Recombinant Human Telomerase reverse transcriptase (TERT), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023391HU	Recombinant Human Telomerase reverse transcriptase (TERT), partial	E.coli