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SLC6A3

SLC6A3基因编码多巴胺转运体,这是一种钠和氯依赖性神经递质转运体家族的成员,其结构包含12个跨膜结构域,并具有特定的糖基化特征。多巴胺转运体主要负责多巴胺的转运和再摄取,从而精确调控突触间隙中多巴胺的浓度,进而影响神经信号的传递。此外,SLC6A3基因的3’UTR包含一个可变数目串联重复序列,其重复次数的变化与多种神经和精神疾病的发生风险相关。在信号通路方面,多巴胺转运体通过调节多巴胺浓度,间接影响多巴胺受体介导的信号传递过程。当多巴胺转运体功能异常时,可能会导致神经信号传递的紊乱,从而引发相关疾病。

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SLC6A3 Antibody

验证数据

WB
CSB-PA021701LA01HU WB

Positive WB detected in: Mouse brain tissue
All lanes: SLC6A3 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69 kDa
Observed band size: 69 kDa

IF
CSB-PA021701LA01HU IF

Immunofluorescent analysis of HepG2 cells using CSB-PA021701LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)


SLC6A3 Antibodies

SLC6A3 for Homo sapiens (Human)