SLC6A3
SLC6A3基因编码多巴胺转运体,这是一种钠和氯依赖性神经递质转运体家族的成员,其结构包含12个跨膜结构域,并具有特定的糖基化特征。多巴胺转运体主要负责多巴胺的转运和再摄取,从而精确调控突触间隙中多巴胺的浓度,进而影响神经信号的传递。此外,SLC6A3基因的3’UTR包含一个可变数目串联重复序列,其重复次数的变化与多种神经和精神疾病的发生风险相关。在信号通路方面,多巴胺转运体通过调节多巴胺浓度,间接影响多巴胺受体介导的信号传递过程。当多巴胺转运体功能异常时,可能会导致神经信号传递的紊乱,从而引发相关疾病。
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验证数据
Positive WB detected in: Mouse brain tissue
All lanes: SLC6A3 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69 kDa
Observed band size: 69 kDa
Immunofluorescent analysis of HepG2 cells using CSB-PA021701LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
SLC6A3 Antibodies
SLC6A3 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA198930 | SLC6A3 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA791171 | SLC6A3 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA021701LA01HU | SLC6A3 Antibody | Human, Mouse | ELISA, WB, IF |
CSB-PA021701LB01HU | SLC6A3 Antibody, HRP conjugated | Human | ELISA |
CSB-PA021701LC01HU | SLC6A3 Antibody, FITC conjugated | Human | |
CSB-PA021701LD01HU | SLC6A3 Antibody, Biotin conjugated | Human | ELISA |