SERPINA1
SERPINA1，即α1-抗胰蛋白酶，是一种主要在肝脏中合成的丝氨酸蛋白酶抑制剂。它是SERPIN家族成员之一，通过与胰蛋白酶等丝氨酸蛋白酶形成稳定的复合物来抑制它们的活性。SERPINA1的作用机制是作为蛋白酶的底物，其活性位点的精氨酸残基与蛋白酶的丝氨酸活性位点发生不可逆的共价结合，从而抑制蛋白酶的活性。这种抑制作用在防止组织损伤和炎症反应中发挥重要作用。SERPINA1在信号传导中的作用涉及到多种生物学过程，包括抗炎、抗凝血和细胞凋亡等。在生物学意义上，SERPINA1对于维护肺健康尤其重要，其遗传性缺乏可导致肺气肿等呼吸系统疾病。此外，SERPINA1的多态性与多种疾病有关，包括肝病和某些类型的癌症。在临床上，SERPINA1的活性水平可作为某些疾病的生物标志物，用于疾病诊断和治疗监测。
热销产品
Recombinant Rat Alpha-1-antiproteinase (Serpina1) (CSB-EP021053RA)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SERPINA1 Antibody (CSB-PA799490)
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA799490(SERPINA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA799490(SERPINA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA799490(SERPINA1 Antibody) at dilution 1/250 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
SERPINA1 Antibodies
SERPINA1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA021053GA01HU | SERPINA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004671 | SERPINA1 Antibody | Human | WB, ELISA |
| CSB-PA006124 | SERPINA1 Antibody | Human | WB, ELISA |
| CSB-PA213215 | SERPINA1 Antibody | Human | ELISA,IHC |
| CSB-PA213997 | SERPINA1 Antibody | Human | ELISA,IHC |
| CSB-PA799490 | SERPINA1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA12565A0Rb | SERPINA1 Antibody | Human | ELISA |
| CSB-PA12565B0Rb | SERPINA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA12565C0Rb | SERPINA1 Antibody, FITC conjugated | Human | |
| CSB-PA12565D0Rb | SERPINA1 Antibody, Biotin conjugated | Human | ELISA |
SERPINA1 for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA021053HD01RA | Serpina1 Antibody, Biotin conjugated | Rat | ELISA |
| CSB-PA021053HA01RA | Serpina1 Antibody | Rat | ELISA |
SERPINA1 Proteins
SERPINA1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP021053RA | Recombinant Rat Alpha-1-antiproteinase (Serpina1) | Yeast |
| CSB-EP021053RA | Recombinant Rat Alpha-1-antiproteinase (Serpina1) | E.coli |
| CSB-BP021053RA CSB-MP021053RA CSB-EP021053RA-B |
Recombinant Rat Alpha-1-antiproteinase (Serpina1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP021053BO CSB-EP021053BO CSB-BP021053BO CSB-MP021053BO CSB-EP021053BO-B |
Recombinant Bovine Alpha-1-antiproteinase (SERPINA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP021053PI CSB-EP021053PI CSB-BP021053PI CSB-MP021053PI CSB-EP021053PI-B |
Recombinant Pig Alpha-1-antitrypsin (SERPINA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Papio anubis (Olive baboon)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP021053ERI CSB-EP021053ERI CSB-BP021053ERI CSB-MP021053ERI CSB-EP021053ERI-B |
Recombinant Papio anubis Alpha-1-antitrypsin (SERPINA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP021053DSU CSB-EP021053DSU CSB-BP021053DSU CSB-MP021053DSU CSB-EP021053DSU-B |
Recombinant Chlorocebus aethiops Alpha-1-antitrypsin (SERPINA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Mus caroli (Ryukyu mouse) (Ricefield mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP328635MUU CSB-EP328635MUU CSB-BP328635MUU CSB-MP328635MUU CSB-EP328635MUU-B |
Recombinant Mus caroli Alpha-1-antiproteinase (Serpina1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Mus saxicola (Brown spiny mouse) (Rock-loving mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP720553MKR CSB-EP720553MKR CSB-BP720553MKR CSB-MP720553MKR CSB-EP720553MKR-B |
Recombinant Mus saxicola Alpha-1-antiproteinase (Serpina1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP732764PYX CSB-EP732764PYX CSB-BP732764PYX CSB-MP732764PYX CSB-EP732764PYX-B |
Recombinant Pongo abelii Alpha-1-antitrypsin (SERPINA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA1 ELISA Kit
SERPINA1 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E11719h | Human α1-Antitrypsin,α1-AT ELISA Kit | serum, plasma | 19.5 nIU/mL |
SERPINA1 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL021053RA | Rat Alpha-1-antitrypsin(SERPINA1) ELISA kit | serum, plasma, tissue homogenates | 15.6 ng/mL |
