RNASEH1
RNASEH1（Ribonuclease H1）是核糖核酸内切酶H1内切酶。RNASEH1的主要功能是在DNA修复过程中起作用，特别是在RNA-DNA杂交物的剪切中。它有助于维持基因组稳定性，通过消除RNA与DNA的杂交，防止不必要的杂交结构的累积，并保持细胞的正常功能。研究表明，RNASEH1的突变或缺陷与一种罕见的遗传性神经系统退行性疾病——Aicardi-Goutières综合征（AGS）相关。AGS通常伴随着神经系统发育异常和免疫系统异常，而RNASEH1的异常可能与此类症状的出现有关。此外，RNASEH1在细胞生物学研究和RNA-DNA杂交相关领域也具有重要的应用潜力。对RNASEH1的深入研究不仅有助于理解细胞的核酸代谢和基因组稳定性的维持，还可能为治疗相关疾病提供新的治疗方法或干预手段。
热销产品
Recombinant Human Ribonuclease H1 (RNASEH1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.
RNASEH1 Antibodies
RNASEH1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA019801GA01HU | RNASEH1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA019801LA01HU | RNASEH1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA019801LB01HU | RNASEH1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019801LC01HU | RNASEH1 Antibody, FITC conjugated | Human | |
| CSB-PA019801LD01HU | RNASEH1 Antibody, Biotin conjugated | Human | ELISA |
RNASEH1 Proteins
RNASEH1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019801MO CSB-EP019801MO CSB-BP019801MO CSB-MP019801MO CSB-EP019801MO-B |
Recombinant Mouse Ribonuclease H1 (Rnaseh1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RNASEH1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019801HU CSB-BP019801HU CSB-MP019801HU CSB-EP019801HU-B |
Recombinant Human Ribonuclease H1 (RNASEH1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019801HU | Recombinant Human Ribonuclease H1 (RNASEH1) | E.coli |
