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Ptk2

PTK2,即蛋白酪氨酸激酶2,别名FAK、FRNK、Fadk、FADK1、p125FAK。它是一种非受体型蛋白酪氨酸激酶,由人体细胞自身的基因编码,广泛表达于多种组织中,包括消化系统、中枢神经系统、眼睛、泌尿生殖系统等。PTK2通过其酪氨酸激酶活性,参与细胞的黏附、迁移和增殖等过程,对细胞群增殖、泛素依赖性蛋白质分解过程以及蛋白质磷酸化具有正向调控作用。PTK2在血管形态发生、神经元生成以及肽基酪氨酸自磷酸化等过程中发挥作用,其活性受多种因素的调控,包括细胞外基质、生长因子和细胞内信号分子等。PTK2的功能异常与多种疾病有关,包括平滑肌瘤、肺小细胞癌和肺动脉高压等,因此,PTK2是药物开发和疾病治疗中的一个潜在靶点 。

热销产品

PTK2 Recombinant Monoclonal Antibody (CSB-RA198162A0HU)

验证数据

CSB-RA198162A0HU

IHC image of CSB-RA198162A0HU diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Ptk2 Antibodies

Ptk2 for Chicken

Ptk2 for Homo sapiens (Human)

Ptk2 Proteins

Ptk2 Proteins for Gallus gallus (Chicken)

Ptk2 Proteins for Mus musculus (Mouse)

Ptk2 Proteins for Rattus norvegicus (Rat)

Ptk2 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Ptk2 Proteins for Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

Ptk2 Proteins for Xenopus laevis (African clawed frog)

Ptk2 ELISA Kit

Ptk2 ELISA Kit for Gallus gallus (Chicken)