Pcsk9

PCSK9，即前蛋白转化酶枯草杆菌蛋白酶/kexin9型，是一种肝脏合成分泌的酶，由PCSK9基因编码。PCSK9的作用机制主要涉及调节血液中低密度脂蛋白受体（LDLR）的水平，通过与LDLR结合促进其在肝脏内降解，从而影响血液中的LDL-胆固醇水平。PCSK9对维持血脂稳态具有重要作用，其功能异常与家族性高胆固醇血症等疾病相关。PCSK9抑制剂的开发为降低心血管疾病风险提供了新的治疗策略。

热销产品

Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9)(D374Y), partial,Biotinylated (CSB-MP017647HU(M)-B)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The purity of PCSK9 was greater than 95% as determined by SEC-HPLC

PCSK9 Recombinant Monoclonal Antibody (CSB-RA259644A0HU)

验证数据

Western Blot
Positive WB detected in: PC-3 whole cell lysate
All lanes: PCSK9 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 75, 21 kDa
Observed band size: 60, 75 kDa

IHC image of CSB-RA259644A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human Proprotein convertase subtilisin/kexin type 9(PCSK9) ELISA kit (CSB-EL017647HU)

验证数据

货号：CSB-EL017647HU

规格：96T/48T

灵敏度：0.11 ng/mL

检测范围：0.45 ng/mL-30 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Pcsk9 Antibody

Pcsk9 Protein

Pcsk9 ELISA Kit

Pcsk9 Antibodies

Pcsk9 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA017647GA01HU	PCSK9 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA638311	PCSK9 Antibody	Human	ELISA,WB
CSB-PA108805	PCSK9 Antibody	Human	ELISA,WB
CSB-PA07039A0Rb	PCSK9 Antibody	Human	ELISA, IHC, IF
CSB-PA07039B0Rb	PCSK9 Antibody, HRP conjugated	Human	ELISA
CSB-PA07039C0Rb	PCSK9 Antibody, FITC conjugated	Human
CSB-PA07039D0Rb	PCSK9 Antibody, Biotin conjugated	Human	ELISA
CSB-PA017647LA01HU	PCSK9 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA017647LB01HU	PCSK9 Antibody, HRP conjugated	Human	ELISA
CSB-PA017647LC01HU	PCSK9 Antibody, FITC conjugated	Human
CSB-PA017647LD01HU	PCSK9 Antibody, Biotin conjugated	Human	ELISA
CSB-RA259644A0HU	PCSK9 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

Pcsk9 Proteins

Pcsk9 Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP017647RA CSB-EP017647RA CSB-BP017647RA CSB-MP017647RA CSB-EP017647RA-B	Recombinant Rat Proprotein convertase subtilisin/kexin type 9 (Pcsk9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Macaca mulatta (Rhesus macaque)

产品货号	产品名称	来源
CSB-YP017647MOW CSB-EP017647MOW CSB-BP017647MOW CSB-MP017647MOW CSB-EP017647MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Colobus guereza (Black-and-white colobus monkey)

产品货号	产品名称	来源
CSB-YP017647DVH CSB-EP017647DVH CSB-BP017647DVH CSB-MP017647DVH CSB-EP017647DVH-B	Recombinant Colobus guereza Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Lagothrix lagotricha (Common woolly monkey)

产品货号	产品名称	来源
CSB-YP017647LNL CSB-EP017647LNL CSB-BP017647LNL CSB-MP017647LNL CSB-EP017647LNL-B	Recombinant Lagothrix lagotricha Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Ateles geoffroyi (Black-handed spider monkey)

产品货号	产品名称	来源
CSB-YP017647AVF CSB-EP017647AVF CSB-BP017647AVF CSB-MP017647AVF CSB-EP017647AVF-B	Recombinant Ateles geoffroyi Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

产品货号	产品名称	来源
CSB-YP017647EQU CSB-EP017647EQU CSB-BP017647EQU CSB-MP017647EQU CSB-EP017647EQU-B	Recombinant Pan paniscus Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Pongo pygmaeus (Bornean orangutan)

产品货号	产品名称	来源
CSB-YP017647EXP CSB-EP017647EXP CSB-BP017647EXP CSB-MP017647EXP CSB-EP017647EXP-B	Recombinant Pongo pygmaeus Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Saguinus labiatus (Red-chested mustached tamarin)

产品货号	产品名称	来源
CSB-YP017647SVY CSB-EP017647SVY CSB-BP017647SVY CSB-MP017647SVY CSB-EP017647SVY-B	Recombinant Saguinus labiatus Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Pan troglodytes (Chimpanzee)

产品货号	产品名称	来源
CSB-YP017647EQV CSB-EP017647EQV CSB-BP017647EQV CSB-MP017647EQV CSB-EP017647EQV-B	Recombinant Pan troglodytes Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Callicebus moloch (Dusky titi monkey)

产品货号	产品名称	来源
CSB-YP017647CYE CSB-EP017647CYE CSB-BP017647CYE CSB-MP017647CYE CSB-EP017647CYE-B	Recombinant Callicebus moloch Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Gorilla gorilla gorilla (Lowland gorilla)

产品货号	产品名称	来源
CSB-YP017647GGZ CSB-EP017647GGZ CSB-BP017647GGZ CSB-MP017647GGZ CSB-EP017647GGZ-B	Recombinant Gorilla gorilla gorilla Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

产品货号	产品名称	来源
CSB-YP017647CYL CSB-EP017647CYL CSB-BP017647CYL CSB-MP017647CYL CSB-EP017647CYL-B	Recombinant Callithrix jacchus Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Macaca nemestrina (Pig-tailed macaque)

产品货号	产品名称	来源
CSB-YP017647MOX CSB-EP017647MOX CSB-BP017647MOX CSB-MP017647MOX CSB-EP017647MOX-B	Recombinant Macaca nemestrina Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

产品货号	产品名称	来源
CSB-YP017647SWC CSB-EP017647SWC CSB-BP017647SWC CSB-MP017647SWC CSB-EP017647SWC-B	Recombinant Saimiri boliviensis boliviensis Proprotein convertase subtilisin/kexin type 9 (PCSK9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP017647MO CSB-EP017647MO CSB-BP017647MO CSB-MP017647MO CSB-EP017647MO-B	Recombinant Mouse Proprotein convertase subtilisin/kexin type 9 (Pcsk9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Pcsk9 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP017647HU CSB-EP017647HU CSB-BP017647HU CSB-MP017647HU CSB-EP017647HU-B	Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005741HU	Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) (Active)	Mammalian cell
CSB-MP017647HU(M)	Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) (D374Y), partial	Mammalian cell
CSB-MP017647HU(M1)	Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) (R194A), partial	Mammalian cell
CSB-MP017647HU(M)-B	Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9)(D374Y), partial,Biotinylated	Mammalian cell