PTHLH
甲状旁腺激素样激素(PTHLH),也称为甲状旁腺激素相关蛋白(PTHrP),是一种多功能肽激素,由3个启动子和9个外显子组成,可因选择性剪接产生3种不同羧基端的变体。最初发现它与恶性肿瘤伴发的高钙血症有关,但随后的研究表明,PTHLH在多种成体和胎儿组织中广泛表达,并参与形态发生、细胞生长与分化的调控以及胎盘钙转运等重要生物学过程。PTHLH通过与其特异性受体PTH1R结合,激活包括G蛋白信号级联、腺苷酸环化酶、磷脂酶C、cAMP、三磷酸肌醇、二酰甘油和Ca2+在内的多种胞内信号通路,这些信号通路在胚胎发育、细胞增殖和凋亡等过程中发挥关键作用。因此,PTHLH不仅在维持机体钙磷平衡中起着至关重要的作用,还在组织发育和疾病发生中扮演着复杂的角色。
热销产品
Human Parathyroid Hormone Related Protein,PTHrP ELISA Kit (CSB-E08649h)
验证数据
货号:CSB-E08649h
规格:96T/48T
灵敏度:7.81 pg/mL
检测范围:31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PTHLH Antibodies
PTHLH for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA018991LD01HU | PTHLH Antibody, Biotin conjugated | Human | ELISA |
CSB-PA018991LA01HU | PTHLH Antibody | Human | ELISA, IHC |
CSB-PA018991GA01HU | PTHLH Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA157934 | PTHLH Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA444792 | PTHLH Antibody | Human,Mouse,Rat | ELISA,IHC |
PTHLH Proteins
PTHLH Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP018991HU CSB-BP018991HU CSB-MP018991HU CSB-EP018991HU-B |
Recombinant Human Parathyroid hormone-related protein (PTHLH),, partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP018991HU | Recombinant Human Parathyroid hormone-related protein (PTHLH), partial | E.coli |
PTHLH ELISA Kit
PTHLH ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E08649h | Human Parathyroid Hormone Related Protein,PTHrP ELISA Kit | serum, plasma, tissue homogenates | 7.81 pg/mL |