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PSEN2

Presenilin-2 is a protein in humans that is encoded by PSEN2 gene. Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

PSEN2 Antibodies

PSEN2 for Homo sapiens (Human)

PSEN2 Proteins

PSEN2 Proteins for Homo sapiens (Human)

PSEN2 Proteins for Rattus norvegicus (Rat)

PSEN2 Proteins for Microcebus murinus (Lesser mouse lemur)

PSEN2 Proteins for Xenopus laevis (African clawed frog)

PSEN2 Proteins for Sus scrofa (Pig)

PSEN2 Proteins for Mus musculus (Mouse)

PSEN2 Proteins for Pongo abelii (Sumatran orangutan)

PSEN2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

PSEN2 Proteins for Gallus gallus (Chicken)

PSEN2 Proteins for Bos taurus (Bovine)