ODC
ODC（鸟氨酸脱羧酶）是一种关键酶，它催化鸟氨酸脱羧生成腐胺，这是多胺合成的重要步骤。ODC由461个氨基酸组成，形成同源二聚体结构，并在细胞内以单体和二聚体形式迅速转换。作为细胞生长所必需的酶，ODC通过产生多胺来稳定新合成的DNA，对DNA结构稳定、DNA双链断裂修复以及抗氧化等方面都具有重要作用。尽管ODC本身不直接参与特定的信号通路，但其在细胞生长和多胺合成中的核心作用可能对某些信号通路产生间接影响，如通过调控Akt/GSK3β/β-catenin等信号通路影响肝癌细胞的增殖、侵袭和迁移等过程。
热销产品
Recombinant Human Ornithine decarboxylase (ODC1) (CSB-EP016269HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .
ODC Antibodies
ODC for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA00535A0Rb | ODC1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA016269GA01HU | ODC1 Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA00535D0Rb | ODC1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA546739 | ODC1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA818178 | ODC1 Antibody | Human,Mouse,Rat | ELISA,IHC |
ODC Proteins
ODC Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP016269HU CSB-BP016269HU CSB-MP016269HU CSB-EP016269HU-B |
Recombinant Human Ornithine decarboxylase (ODC1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP016269HU | Recombinant Human Ornithine decarboxylase (ODC1) | E.coli |
